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Final odds, predictions for WVU football's Week 4 showdown with Oklahoma State

Can the Mountaineers stay undefeated and move to 4-0 against the Cowboys?
ByJoseph Smith|
Sep 19, 2026; Charlotte, North Carolina, USA; West Virginia Mountaineers defensive end David Afogho (99) celebrates after sacking Virginia Cavaliers quarterback Beau Pribula (7) during the second quarter at Bank of America Stadium. Mandatory Credit: Ben Queen-Imagn Images
Sep 19, 2026; Charlotte, North Carolina, USA; West Virginia Mountaineers defensive end David Afogho (99) celebrates after sacking Virginia Cavaliers quarterback Beau Pribula (7) during the second quarter at Bank of America Stadium. Mandatory Credit: Ben Queen-Imagn Images | IMAGN IMAGES via Reuters Connect

The West Virginia Mountaineers are looking to keep the momentum rolling on Saturday night against Oklahoma State in what will serve as the Big 12 opener for both schools.

West Virginia is riding high after beating a then-ranked Virginia team last week in a neutral-site game in Charlotte, and are prepared to return home to what is expected to be a rowdy, packed crowd at Milan Puskar Stadium.

With two Big 12 teams that were projected as turnaround programs ahead of the season set to clash after picking up Top 25 wins in non-conference play, let's take a look at the finals odds and predictions for the game.

Final betting odds for West Virginia vs. Oklahoma State

The odds continue to tilt in West Virginia's favor, as they've jumped up a half-point in the past 24 hours to be two-point favorites entering the game. The over/under is continuing to rise as well, and it's now set at 61.5 points.

Game odds refresh periodically and are subject to change.

If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

Final predictions for West Virginia vs. Oklahoma State

The Mountaineers seem to be the national favorites among the media too – just look at the College GameDay crew, who did something that never really happens this morning andunanimously selectedWest Virginia as their pick to win against Oklahoma State.

What do we think? Well, last week said a lot about what we can expect out of the Mountaineers, and it showed they can compete with – and beat – high level Power 4 competition. That gives us a lot of confidence in their ability to beat a rebuilding Oklahoma State squad.

But achieving that task will not be easy, as the Cowboys have a dominant win against a Top 25 opponent in Oregon under their belts. Their quarterback, Drew Mestemaker, is experienced in his coach's system, playing for him last year at North Texas, and is widely considered a top NFL prospect. Expect him to give West Virginia's secondary, which struggled against Coast Carolina, plenty of trouble.

In the end, this couldbe good old-fashioned Big 12 shootout, but expect a rowdy night-crowd at Milan Puskar Stadium and West Virginia's ability to attack both the ground and the air to be a deciding factor.

HailWV Prediction for West Virginia vs. Oklahoma State:

West Virginia: 45

Oklahoma State: 42

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